NRF2 activator A-1396076 ameliorates inflammation in autoimmune disease models by inhibiting antigen dependent T cell activation
Author:
Funder
AbbVie
Publisher
Elsevier BV
Subject
Immunology,Immunology and Allergy
Reference35 articles.
1. Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genes in macrophages;Ishii;J. Biol. Chem.,2000
2. Discovery of the negative regulator of Nrf2, Keap1: a historical overview;Itoh;Antioxidants Redox Signal.,2010
3. The Keap1 BTB/POZ dimerization function is required to sequester Nrf2 in cytoplasm;Zipper;J. Biol. Chem.,2002
4. Keap1 recruits Neh2 through binding to ETGE and DLG motifs: characterization of the two-site molecular recognition model;Tong;Mol. Cell Biol.,2006
5. Dimerization of substrate adaptors can facilitate cullin-mediated ubiquitylation of proteins by a "tethering" mechanism: a two-site interaction model for the Nrf2-Keap1 complex;McMahon;J. Biol. Chem.,2006
Cited by 6 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. The role of Nrf2 in immune cells and inflammatory autoimmune diseases: a comprehensive review;Expert Opinion on Therapeutic Targets;2024-09-10
2. A double whammy for KEAP1;Cell Chemical Biology;2024-06
3. Transcription Factor NRF2 in Shaping Myeloid Cell Differentiation and Function;Advances in Experimental Medicine and Biology;2024
4. Beyond Antioxidation: Keap1–Nrf2 in the Development and Effector Functions of Adaptive Immune Cells;ImmunoHorizons;2023-04-01
5. Recent Advances in Understanding Nrf2 Agonism and Its Potential Clinical Application to Metabolic and Inflammatory Diseases;International Journal of Molecular Sciences;2022-03-05
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3