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Novel solid dispersions of benznidazole: Preparation, dissolution profile and biological evaluation as alternative antichagasic drug delivery system

  • Published:2015-02 Issue: Volume:149 Page:84-91
  • ISSN:0014-4894
  • Container-title:Experimental Parasitology
  • language:en
  • Short-container-title:Experimental Parasitology

Author:

Fonseca-Berzal Cristina,Palmeiro-Roldán Ricardo,Escario José A.,Torrado Susana,Arán Vicente J.,Torrado-Santiago Santiago,Gómez-Barrio Alicia

Funder

Spanish Ministries of Science and Innovation

Foreign Affairs and Cooperation

Universidad Complutense de Madrid

UCM-BSCH Research Group ‘Terapia Antiparasitaria’

Publisher

Elsevier BV

Subject

Immunology,General Medicine,Parasitology,Infectious Diseases

Reference47 articles.

1. Therapeutic activity and criterion of cure on mice experimentally infected with Trypanosoma cruzi;Brener;Rev. Inst. Med. Trop. São Paulo,1962

2. Efficient technique for screening drugs for activity against Trypanosoma cruzi using parasites expressing β-galactosidase;Buckner;Antimicrob. Agents Chemother,1996

3. Long term evaluation of etiological treatment of Chagas disease with benznidazole;Cançado;Rev. Inst. Med. Trop. São Paulo,2002

4. Toxic side effects of drugs used to treat Chagas’ disease (American trypanosomiasis);Castro;Hum. Exp. Toxicol,2006

5. Effects of bile salts on gastrointestinal absorption of pravastatin;Chun;J. Pharm. Sci,2012
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