Copper salisylaldoxime (CuSAL) imparts protective efficacy against visceral leishmaniasis by targeting Leishmania donovani topoisomerase IB-Reference-Cited by-同舟云学术

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Copper salisylaldoxime (CuSAL) imparts protective efficacy against visceral leishmaniasis by targeting Leishmania donovani topoisomerase IB

Published:2017-04 Issue: Volume:175 Page:8-20
ISSN:0014-4894
Container-title:Experimental Parasitology
language:en
Short-container-title:Experimental Parasitology

Author:

Singh Manoj Kumar,Bhaumik Siddhartha Kumar,Karmakar Subir,Paul Joydeep,Sawoo Sudeshna,Majumder Hemanta K.,Roy Amit

Publisher

Elsevier BV

Subject

Immunology,General Medicine,Parasitology,Infectious Diseases

Reference31 articles.

1. Kinetoplastid Membrane Protein-11 DNA Vaccination Induces Complete Protection against Both Pentavalent Antimonial-Sensitive and -Resistant Strains ofLeishmania donovaniThat Correlates with Inducible Nitric Oxide Synthase Activity and IL-4 Generation: Evidence for Mixed Th1- and Th2-Like Responses in Visceral Leishmaniasis

2. Complete protection against experimental visceral leishmaniasis with complete soluble antigen from attenuated Leishmaniadonovanipromastigotes involves Th1-immunity and down-regulation of IL-10;Bhaumik;Eur. J. Immunol.,2009

3. DNA topoisomerases: structure, function, and mechanism;Champoux;Annu. Rev. Biochem.,2001

4. Dihydrobetulinic acid induces apoptosis in Leishmaniadonovani by targeting DNA topoisomerase I and II: implications in antileishmanial therapy;Chowdhury;Mol. Med.,2003

5. Limited activity of bacterial DNA topoisomerase II inhibitors against Leishmaniadonovani and Trypanosomacruziamastigotes in vitro;Croft;Trans. R. Soc. Trop. Med. Hyg.,1988

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