Anti-leishmanial effect of spiro dihydroquinoline-oxindoles on volume regulation decrease and sterol biosynthesis of Leishmania braziliensis

Author:

Leañez Jacques,Nuñez Jorge,García-Marchan Yael,Sojo Felipe,Arvelo Francisco,Rodriguez Daniel,Buscema IgnacioORCID,Alvarez-Aular AlvaroORCID,Bello Forero Josué S.,Kouznetsov Vladímir V.,Serrano-Martín Xenón

Funder

Fondo Nacional de Ciencia Tecnología e Innovación

Ministerio del Poder Popular para Educación Universitaria, Ciencia y Tecnología

Colombian Institute for Science and Research (COLCIENCIAS)

Publisher

Elsevier BV

Subject

Immunology,General Medicine,Parasitology,Infectious Diseases

Reference53 articles.

1. Synthesis, docking studies and anti-inflammatory activity of some 2-amino-5,6,7,8-tetrahydroquinoline-3-carbonitriles and related compounds;Abd El-Salam;Pharmazie,2004

2. The pharmacological inhibition of sterol biosynthesis in Leishmania is counteracted by enhancement of LDL endocytosis;Andrade-Neto;Acta Trop.,2011

3. Anti-leishmanial evaluation of C2-aryl quinolines: mechanistic insight on bioenergetics and sterol biosynthetic pathway of Leishmania braziliensis;Bompart;Bioorg. Med. Chem.,2013

4. The 8-aminoquinoline analogue sitamaquine causes oxidative stress in Leishmania donovani promastigotes by targeting succinate dehydrogenase;Carvalho;Antimicrob. Agents Chemother.,2011

5. Chemotherapy of trypanosomiases and leishmaniasis;Croft;Trends Parasitol.,2005

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