Lung cytochrome P450-dependent benzyloxyphenoxazone debenzylase and ethoxyphenoxazone deethylase activities in total microsomal and isolated alveolar type II cells: Responses to changes in assay conditions with special reference to non-linear dependence at low enzyme concentration

Author:

Rabovsky J.,Judy D.J.,Goddard M.,Pailes W.H.,Castranova V.

Publisher

Elsevier BV

Subject

Biochemistry

Reference18 articles.

1. Cytochrome P450 LM2 Reduction: substrate effects on the rate of reductaseLM2 association;Backers;J. biol. Chem,1989

2. A comparative study of the hepatic and pulmonary microsomal mixed-function oxidase systems in the rabbit;Bend;J. Pharmac. Exp. Ther.,1972

3. Characteristics of a microsomal cytochrome P-448-mediated reaction: ethoxyresorufin-O-deethylation;Burke;Drug Met. Dispos,1977

4. Stability of rat lung and liver microsomal cytochrome P450 enzyme activities to storage: purified microsomal fraction, postmitochondrial fraction and whole tissue;Danner-Rabovsky;J. Toxic. Environ. Health,1982

5. Immunogenicity of Liposomal Model Membranes;Kinsky;Ann. N.Y. Acad. Sci.,1978

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1. Metabolism of styrene by mouse and rat isolated lung cells;Toxicological Sciences;1999-10-01

2. Pulmonary Activation and Toxicity of Cyclopentadienyl Manganese Tricarbonyl;Toxicology and Applied Pharmacology;1996-02

3. Respiratory Tract Uptake of Inhalants and Metabolism of Xenobiotics;Annual Review of Pharmacology and Toxicology;1993-04

4. Cytochrome P-450-dependent metabolism in alveolar type II epithelial cells: modulation by platelet-activating factor;Biochimica et Biophysica Acta (BBA) - Molecular Cell Research;1991-11

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