The need to show minimum clinically important differences in Alzheimer's disease trials

Author:

Liu Kathy Y,Schneider Lon S,Howard Robert

Publisher

Elsevier BV

Subject

Biological Psychiatry,Psychiatry and Mental health

Reference27 articles.

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3. Failure to demonstrate efficacy of aducanumab: an analysis of the EMERGE and ENGAGE trials as reported by Biogen, December 2019;Knopman;Alzheimers Dement,2020

4. Department of Health and Human Services, Public Health Service, Food and Drug Administration. US Food and Drug Administration Peripheral and Central Nervous System Drugs Advisory Committee meeting; Rockville, MD, USA; July 7, 1989.

5. The ASA statement on p-values: context, process, and purpose;Wasserstein;Am Stat,2016

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