Safety and efficacy of erythropoietin for the treatment of patients with optic neuritis (TONE): a randomised, double-blind, multicentre, placebo-controlled study

Author:

Lagrèze Wolf A,Küchlin Sebastian,Ihorst Gabriele,Grotejohann Birgit,Beisse Flemming,Volkmann Martin,Heinrich Sven P,Albrecht Philipp,Ungewiss Judith,Wörner Michael,Hug Martin J,Wolf Sebastian,Diem Ricarda,Albrecht Philipp,Aktas Orhan,Beck Anna,Beckmann Anke,Beisse Flemming,Berthele Achim,Bönig Lena,Diem Ricarda,Elflein Heike,Fitzner Dirk,Fleischer Vinzenz,Gingele Stefan,Grotejohann Birgit,Guthoff Tanja,Guthoff Rainer,Hartmann Kathrin,Hassenstein Andrea,Heesen Christoph,Hein Katharina,Heinrich Sven P.,Hufendiek Karsten,Hug Martin J.,Huhn Konstantin,Hümmert Martin W.,Ihorst Gabriele,Klopfer Matthias,Kruse Friedrich E.,Küchlin Sebastian,Kümpfel Tania,Lagrèze Wolf A.,Linker Ralf A.,Lorenz Katrin,Molnár Fanni E.,Mulazzani Elisabeth,Müller Marcus,Nickel Florian T.,Noll Marion,Pielen Amelie,Pitz Susanne,Rauer Sebastian,Reich Michael,Rosenkranz Sina,Schwenkenbecher Philipp,Siller Nelly,Skripuletz Thomas,Stangel Martin,Stellmann Jan-Patrick,Stürner Klarissa,Sühs Kurt-Wolfram,Ungewiss Judith,Uphaus Timo,van Oterendorp Christian,Volkmann Martin,Wabbels Bettina,Wilhelm Helmut,Wolf Sebastian,Wörner Michael,Ziemann Ulf,Zipp Frauke

Funder

BMBF Bonn

Publisher

Elsevier BV

Subject

Neurology (clinical)

Reference34 articles.

1. Multiple sclerosis risk after optic neuritis: final optic neuritis treatment trial follow-up;Arch Neurol,2008

2. A serial study of retinal changes following optic neuritis with sample size estimates for acute neuroprotection trials;Henderson;Brain,2010

3. Corticosteroids for treating optic neuritis;Gal;Cochrane Database Syst Rev,2015

4. Evidence that erythropoietin modulates neuroinflammation through differential action on neurons, astrocytes, and microglia;Bond;Front Immunol,2014

5. Erythropoietin protects CA1 neurons against global cerebral ischemia in rat: potential signaling mechanisms;Zhang;J Neurosci Res,2006

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