Credulity of exploratory trials for cerebral cavernous malformations

Author:

Shenkar Robert,Awad Issam A

Publisher

Elsevier BV

Subject

Neurology (clinical)

Reference8 articles.

1. Cerebral cavernous malformation: from mechanism to therapy;Snellings;Circ Res,2021

2. Effect of simvastatin on permeability in cerebral cavernous malformation type 1 patients: results from a pilot small randomized controlled clinical trial;Mabray;Transl Stroke Res,2020

3. Atorvastatin treatment of cavernous angiomas with symptomatic hemorrhage exploratory proof of concept (AT CASH EPOC) trial;Polster;Neurosurgery,2019

4. Safety and activity of propranolol for treatment of familial cerebral cavernous malformations (Treat_CCM): a randomised, open-label, blinded-endpoint, phase 2 pilot trial;Lanfranconi;Lancet Neurol,2022

5. Propranolol as therapy for cerebral cavernous malformations: a cautionary note;Shenkar;J Transl Med,2022

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