Synthesis of four diastereoisomers at carbons 24 and 25 of 3 alpha,7 alpha,12 alpha,24-tetrahydroxy-5 beta-cholestan-26-oic acid, intermediates of bile acid biosynthesis.

Author:

Une M,Nagai F,Kihira K,Kuramoto T,Hoshita T

Publisher

Elsevier BV

Subject

Cell Biology,Endocrinology,Biochemistry

Reference13 articles.

1. The Biology of Cholesterol and Related Steroids;Myant,1981

2. Synthesis of 3a,7a, 12a,24£-tetrahydroxy-coprostanic acid;Inai;J. Biochem. (Tokyo).,1964

3. Metabolism of 3a,7a,12a,24-tetrahydroxy-5ß-cholestanoic acid in the guinea pig;Tanaka;Hiroshima J. Med. Sci.,1965

4. The formation of bile acids from cholesterol. The conversion of 5ß-cholestane- 3a,7a,12a-triol-26-oic acid to cholic acid via 5ß-cholestane-3a,7a,12a,24***-tetraol-26-oic acid I by rat liver;Masui;J. Biol. Chem.,1966

5. Reversedphase high-performance liquid chromatographic separation and quantification of individual human bile acids;Mingrone;J. Chromatogr.,1980

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