Possible involvement of endogenous nociceptin/orphanin FQ in the pain-related behavioral responses induced by its own metabolite, nociceptin/orphanin FQ(14

Possible involvement of endogenous nociceptin/orphanin FQ in the pain-related behavioral responses induced by its own metabolite, nociceptin/orphanin FQ(14–17)

Published:2007-03 Issue:3 Volume:28 Page:670-677
ISSN:0196-9781
Container-title:Peptides
language:en
Short-container-title:Peptides

Author:

Watanabe Hiroyuki,Mizoguchi Hirokazu,Orito Tohru,Katsuyama Sou,Yonezawa Akihiko,Watanabe Chizuko,Sakurada Tsukasa,Sakurada Shinobu

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Endocrinology,Physiology,Biochemistry

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1. Discovery of small-molecule nonpeptide antagonists of nociceptin/orphanin FQ receptor: The studies of design, synthesis, and structure–activity relationships for (4-arylpiperidine substituted-methyl)-[bicyclic (hetero)cycloalkanobenzene] derivatives;European Journal of Medicinal Chemistry;2016-05

2. Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: Design, synthesis, and structure–activity relationships;Bioorganic & Medicinal Chemistry;2010-11

3. Nociceptin and its metabolite attenuate U0126-induced memory impairment through a nociceptin opioid peptide (NOP) receptor-independent mechanism;Neurobiology of Learning and Memory;2010-03

4. Distinct effects of nociceptin analogs on scopolamine-induced memory impairment in mice;European Journal of Pharmacology;2009-01

5. Endogenous opiates and behavior: 2007;Peptides;2008-12