Developing an RNase-free bioprocess to produce pharmaceutical-grade plasmid DNA using selective precipitation and membrane chromatography

Author:

Zhong Luyang,Srirangan Kajan,Scharer Jeno,Moo-Young Murray,Fenner Drew,Crossley Lisa,Howie Honeyman C.,Suen Shing-Yi,Perry Chou C.

Funder

Canada Research Chairs

Natural Sciences and Engineering Research Council of Canada

Publisher

Elsevier BV

Subject

Filtration and Separation,Analytical Chemistry

Reference31 articles.

1. Using DNA as a drug – Bioprocessing and delivery strategies;Han;Chem. Eng. Res. Des.,2009

2. Downstream processing of plasmid DNA for gene therapy and DNA vaccine applications;Ferreira;Trends Biotechnol.,2000

3. Approaches to enhance the efficacy of DNA vaccines;Manoj;Cr. Rev. Cl Lab. Sc.,2004

4. DNA vaccines: a key for inducing long-term cellular immunity;Gurunathan;Curr. Opin. Biotech.,2000

5. Gene therapy clinical trials worldwide 1989–2004 — An overview;Edelstein;J. Gene Med.,2004

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