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An efficient multiple-stage procedure for phase II clinical trials that have high response rate objectives

  • Published:1994-08 Issue:4 Volume:15 Page:277-283
  • ISSN:0197-2456
  • Container-title:Controlled Clinical Trials
  • language:en
  • Short-container-title:Controlled Clinical Trials

Author:

Shande Chen ,Seng-jaw Soong ,Wheeler Richard H.

Publisher

Elsevier BV

Subject

Pharmacology

Reference14 articles.

1. The determination of the number of patients required in a follow-up trial of a new chemotherapeutic agent;Gehan;J Chronic Dis,1961

2. An application of decision theory to phase II clinical trials in cancer;Sylvester,1977

3. Two stage screening designs applied to chemical screening programs with binary data;Elashoff;Annu Rev Biophys Bioeng,1976

4. Two stage plans for patient accrual in phase II cancer clinical trials;Lee;Cancer Treat Rep,1979

5. Designs for group sequential phase II clinical trials;Chang;Biometrics,1987

Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Bayesian single‐to‐double arm transition design using both short‐term and long‐term endpoints;Pharmaceutical Statistics;2023-02-08

2. Re-formulating Gehan’s design as a flexible two-stage single-arm trial;BMC Medical Research Methodology;2019-01-28

3. Exploratory trials in mental health: anything to learn from other disciplines?;Evidence Based Mental Health;2017-01-10

4. References;A Practical Guide to Designing Phase II Trials in Oncology;2014-04-11

5. A class of confidence intervals for sequential phase II clinical trials with binary outcome;Journal of Applied Statistics;2011-03
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