A Synthetic Lethal Interaction between K-Ras Oncogenes and Cdk4 Unveils a Therapeutic Strategy for Non-small Cell Lung Carcinoma-Reference-Cited by-同舟云学术

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A Synthetic Lethal Interaction between K-Ras Oncogenes and Cdk4 Unveils a Therapeutic Strategy for Non-small Cell Lung Carcinoma

Published:2010-07 Issue:1 Volume:18 Page:63-73
ISSN:1535-6108
Container-title:Cancer Cell
language:en
Short-container-title:Cancer Cell

Author:

Puyol Marta,Martín Alberto,Dubus Pierre,Mulero Francisca,Pizcueta Pilar,Khan Gulfaraz,Guerra Carmen,Santamaría David,Barbacid Mariano

Publisher

Elsevier BV

Subject

Cancer Research,Cell Biology,Oncology

Reference35 articles.

1. Systematic RNA interference reveals that oncogenic KRAS-driven cancers require TBK1;Barbie;Nature,2009

2. Mice thrive without Cdk4 and Cdk2;Barrière;Mol. Oncol.,2007

3. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints;Bartkova;Nature,2006

4. A gene-alteration profile of human lung cancer cell lines;Blanco;Hum. Mutat.,2009

5. Cdk2 suppresses cellular senescence induced by the c-myc oncogene;Campaner;Nat. Cell Biol.,2010

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