AKT and cancer—Is it all mTOR?
Author:
Publisher
Elsevier BV
Subject
Cancer Research,Cell Biology,Oncology
Reference13 articles.
1. The deficiency of Akt1 is sufficient to suppress tumor development in Pten+/− mice
2. A dual PI3 kinase/mTOR inhibitor reveals emergent efficacy in glioma
3. The TSC1-2 tumor suppressor controls insulin–PI3K signaling via regulation of IRS proteins
4. Reduction in the requirement of oncogenic Ras signaling to activation of PI3K/AKT pathway during tumor maintenance
5. Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2
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