ABT-199: Taking Dead Aim at BCL-2
Author:
Publisher
Elsevier BV
Subject
Cancer Research,Cell Biology,Oncology
Reference10 articles.
1. Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members
2. Targeting the B-Cell Lymphoma/Leukemia 2 Family in Cancer
3. Decreased mitochondrial apoptotic priming underlies stroma-mediated treatment resistance in chronic lymphocytic leukemia
4. Chronic lymphocytic leukemia requires BCL2 to sequester prodeath BIM, explaining sensitivity to BCL2 antagonist ABT-737
5. BH3 Profiling Identifies Three Distinct Classes of Apoptotic Blocks to Predict Response to ABT-737 and Conventional Chemotherapeutic Agents
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