Promiscuity and diversity in 3-ketosteroid reductases

Author:

Penning Trevor M.,Chen Mo,Jin Yi

Funder

NIH

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Endocrinology,Molecular Biology,Molecular Medicine,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference51 articles.

1. Enzymatic mechanisms of hormone metabolism 1. Oxidation and reduction of the steroid nucleus;Tomkins;Recent Prog. Horm. Res.,1956

2. A mammalian 3α-hydroxysteroid dehydrogenase;Tomkins;J. Biol. Chem.,1956

3. Steroid 5α-reductase two genes/two enzymes;Russell;Annu. Rev. Biochem.,1994

4. Novel 5α-steroid reductase (SRD5A3, type-3) is overexpressed in hormone-refractory prostate cancer;Uemura;Cancer Sci.,2008

5. Cloning and expression of cDNA of human Δ4-3-oxosteroid-5β-reductase and substrate specificity of the expressed enzyme;Kondo;Eur. J. Biochem.,1994

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