16-Picolyl-androsterone derivative exhibits potent 17β-HSD3 inhibitory activity, improved metabolic stability and cytotoxic effect on various cancer cells: Synthesis, homology modeling and docking studies-Reference-Cited by-同舟云学术

16-Picolyl-androsterone derivative exhibits potent 17β-HSD3 inhibitory activity, improved metabolic stability and cytotoxic effect on various cancer cells: Synthesis, homology modeling and docking studies

Published:2021-06 Issue: Volume:210 Page:105846
ISSN:0960-0760
Container-title:The Journal of Steroid Biochemistry and Molecular Biology
language:en
Short-container-title:The Journal of Steroid Biochemistry and Molecular Biology

Author:

Cortés-Benítez Francisco^ORCID,Roy Jenny,Perreault Martin,Maltais René,Poirier Donald^ORCID

Funder

Prostate Cancer Canada

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Endocrinology,Molecular Biology,Molecular Medicine,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference73 articles.

1. Analysis and characteristics of multiple types of human 17β-hydroxysteroid dehydrogenase;Luu-The;J. Steroid Biochem. Mol. Biol.,2001

2. Male pseudohermaphroditism caused by mutations of testicular 17β-hydroxysteroid dehydrogenase 3;Geissler;Nat. Genet.,1994

3. 17β-Hydroxysteroid dehydrogenases: Physiological roles in health and disease;Moghrabi;TEM,1998

4. Overview of steroidogenic enzymes in the pathway from cholesterol to active steroid hormones;Payne;Endocr. Rev.,2004

5. Intracrinology;Labrie;Mol. Cell. Endocrinol.,1991

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