Structure-function relationships for the selective inhibition of human 3β-hydroxysteroid dehydrogenase type 1 by a novel androgen analog-Reference-Cited by-同舟云学术

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Structure-function relationships for the selective inhibition of human 3β-hydroxysteroid dehydrogenase type 1 by a novel androgen analog

Published:2017-11 Issue: Volume:174 Page:257-264
ISSN:0960-0760
Container-title:The Journal of Steroid Biochemistry and Molecular Biology
language:en
Short-container-title:The Journal of Steroid Biochemistry and Molecular Biology

Author:

Pham Jenny H.,Will Catherine M.,Mack Vance L.,Halbert Matthew,Conner Edward Alexander,Bucholtz Kevin M.,Thomas James L.

Funder

Mercer University School of Medicine

Mercer University Seed

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Endocrinology,Molecular Biology,Molecular Medicine,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference34 articles.

1. Structure and expression of a new complementary DNA encoding the almost exclusive 3β-hydroxysteroid dehydrogenase/Δ5-Δ4-isomerase in human adrenals and gonads;Rhéaume;Mol. Endocrinol.,1991

2. The molecular biology, biochemistry, and physiology of human steroidogenesis and its disorders;Miller;Endocr. Rev.,2011

3. Identification of key amino acids responsible for the substantiality higher affinities type 1 3β-hydroxysteroid dehydrogenase/isomerase (3βHSD1) for substrates, coenzymes and inhibitors relative to 3βHSD2;Thomas;J. Biol. Chem.,2005

4. Breast cancer and the role of cytokines in the regulating estrogen synthesis: an emerging hypothesis;Reed;Endo Rev,1997

5. The selective estrogen enzyme modulators in breast cancer;Pasqualini,2002

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