11-Oxygenated androgen precursors are the preferred substrates for aldo-keto reductase 1C3 (AKR1C3): Implications for castration resistant prostate cancer-Reference-Cited by-同舟云学术

11-Oxygenated androgen precursors are the preferred substrates for aldo-keto reductase 1C3 (AKR1C3): Implications for castration resistant prostate cancer

Published:2018-10 Issue: Volume:183 Page:192-201
ISSN:0960-0760
Container-title:The Journal of Steroid Biochemistry and Molecular Biology
language:en
Short-container-title:The Journal of Steroid Biochemistry and Molecular Biology

Author:

Barnard Monique,Quanson Jonathan L.^ORCID,Mostaghel Elahe,Pretorius Elzette,Snoep Jacky L.,Storbeck Karl-Heinz^ORCID

Funder

National Research Foundation of South Africa

NRF/DST

Medical Research Council of South Africa

NIH Pacific Northwest Prostate Cancer SPORE

NIH

DOD

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Endocrinology,Molecular Biology,Molecular Medicine,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference43 articles.

1. Androgen receptors in hormone-dependent and castration-resistant prostate cancer;Shafi;Pharmacol. Ther.,2013

2. The androgen axis in recurrent prostate cancer;Mohler;Clin. Cancer Res.,2004

3. Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer;Attard;J. Clin. Oncol.,2009

4. Abiraterone and increased survival in metastatic prostate cancer;de Bono;N. Engl. J. Med.,2011

5. Phase I clinical trial of a selective inhibitor of CYP17, abiraterone acetate, confirms that castration-resistant prostate cancer commonly remains hormone driven;Attard;J. Clin. Oncol.,2008

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5. Prostate cancer androgen biosynthesis relies solely on CYP17A1 downstream metabolites;The Journal of Steroid Biochemistry and Molecular Biology;2024-02