Effect of mutations in porcine CYB5A and CYP17A1 on the metabolism of pregnenolone

Author:

Squires E. James,Gray Matthew A.,Lou Yanping

Funder

Natural Sciences and Engineering Research Council of Canada

Publisher

Elsevier BV

Subject

Cell Biology,Clinical Biochemistry,Endocrinology,Molecular Biology,Molecular Medicine,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference26 articles.

1. 16-Unsaturated C19 steroids: a review of their chemistry, biochemistry and possible physiological role;Gower;J. Steroid Biochem.,1972

2. Determination of 5-androst-16-ene-3-one, a boar taint steroid in pigs, with reference to relationship to testosterone;Claus;J. Anim. Sci.,1971

3. Welfare aspects of the castration of piglets. Scientific report of the Scientific Panel for Animal Health and Welfare;Gunn;Eur. Food Saf. Authority J.,2004

4. The cationic charges on arg 347, arg358 and arg449 of human cytochrome P450c17 (CYP17A1) are essential for the enzyme’s cytochrome b5-dependent acyl-carbon cleavage activities;Lee-Robichaud;J. Steroid Biochem. Mol. Biol.,2004

5. The diverse chemistry of cytochrome P450 17A1 (P450c17, CYP17A1A1);Yoshimoto;J. Steroid Biochem. Mol. Biol.,2015

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