Polygenic risk score in comparison with C-reactive protein for predicting incident coronary heart disease

Author:

Aday Aaron W.ORCID,Bagheri Minoo,Vaitinadin Nataraja Sarma,Mosley Jonathan D.,Wang Thomas J.

Funder

American Heart Association

Boston University

National Institutes of Health

National Human Genome Research Institute

National Heart, Lung, and Blood Institute

Publisher

Elsevier BV

Subject

Cardiology and Cardiovascular Medicine

Reference57 articles.

1. ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American heart association task force on practice guidelines;Goff;Circulation,2013

2. Validation of the atherosclerotic cardiovascular disease pooled cohort risk Equations;Muntner;JAMA,2014

3. Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations;Khera;Nat. Genet.,2018

4. Genetic risk, adherence to a healthy lifestyle, and coronary disease;Khera;N. Engl. J. Med.,2016

5. Genomic risk prediction of coronary artery disease in 480,000 adults;Inouye;J. Am. Coll. Cardiol.,2018

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