STAR-121: A Phase III Randomized Study of Domvanalimab and Zimberelimab in Combination With Chemotherapy Versus Pembrolizumab With Chemotherapy in Untreated Metastatic Non–Small Cell Lung Cancer With No Actionable Gene Alterations

Author:

Rodriguez-Abreu Delvys,Bosch-Barrera Joaquim,Gray Jhanelle E.,Ahn Myung-Ju,Johnson Melissa,Yu Xinwei,Mohammad Saad,Chen Xueying,Todd Trever,Kim Jongseok,Reck Martin

Publisher

Elsevier BV

Subject

Cancer Research,Pulmonary and Respiratory Medicine,Oncology

Reference17 articles.

1. Non-oncogene-addicted metastatic non-small-cell lung cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up;Hendriks;Ann Oncol,2023

2. Referenced with permission from the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines®) for non-small cell lung cancer V.5.2023. © National Comprehensive Cancer Network, Inc. 2023. All rights reserved. Accessed November 19, 2023.

3. Clinical pattern of failure after a durable response to immune checkpoint inhibitors in non-small cell lung cancer patients;Heo;Sci Rep,2021

4. Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses;Banta;Immunity,2022

5. Co-inhibition of TIGIT and PD-1/PD-L1 in cancer immunotherapy: mechanisms and clinical trials;Chu;Mol Cancer,2023

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