1. Clinical trials and rare diseases: a way out of a conundrum;Lilford;BMJ,1995
2. Regulation (EC) No 141/2000 of the European Parliament and of the Council on Orphan Medicinal Products of 16 December 1999 and Commission Regulation (EC) No 847/2000 of 27 April 2000;Off J Euro Comm,2000
3. Stiripentol in severe myoclonic epilepsy in infancy: a randomised placebo-controlled syndrome-dedicated trial;Chiron;Lancet,2000
4. Note for guidance on statistical principles in clinical trials;Anon,1998
5. Fundamentals of clinical trials;Friedman,1998