Pegcetacoplan for the treatment of geographic atrophy secondary to age-related macular degeneration (OAKS and DERBY): two multicentre, randomised, double-masked, sham-controlled, phase 3 trials

Author:

Heier Jeffrey S,Lad Eleonora M,Holz Frank G,Rosenfeld Philip J,Guymer Robyn H,Boyer David,Grossi Federico,Baumal Caroline R,Korobelnik Jean-Francois,Slakter Jason S,Waheed Nadia K,Metlapally Ravi,Pearce Ian,Steinle Nathan,Francone Anibal A,Hu Allen,Lally David R,Deschatelets Pascal,Francois Cedric,Bliss Caleb,Staurenghi Giovanni,Monés Jordi,Singh Rishi P,Ribeiro Ramiro,Wykoff Charles C,Cole Abosede O,Gerstenblith Adam T,Kotagiri Ajay,Edwards Albert O,Zambrano Alberto D,Eaton Alexander M,Rubowitz Alexander,Lyon Alice T,Chiang Allen,Ho Allen,Hu Allen Y,Guerami Amir H,Dessouki Amr L,de Carvalho André Corrêa Maia,Emanuelli Andrés,Chang Andrew A,Antoszyk Andrew N,Francone Anibal Andrés,Prasad Anita,Wolf Armin,Khanani Arshad M,Abbey Ashkan Michael,Moulana Asma,Wihelm Barbara,Sikorski Bartosz L,Kuppermann Baruch D,Wolff Benjamin,Jewart Brian H,Do Brian K,Chan-Kai Brian T,Mein Calvin,Hoyng Carel B,Awh Carl C,Regillio Carl,Zeolite Carlos,Baumal Caroline R,Creuzot-Garcher Catherine,Maury Catherine Français,Wykoff Charles C,Newell Charles K,Jhaveri Chirag,Lohmann Chris P,Dinah Christiana B,Ma Colin,Crawford Courtney,Parke D Wilkin,Lavinsky Daniel,Roth Daniel,Pieramici Dante J,Moshfeghi Darius M,Levin Darrin,Saperstein David A,Brown David,Gaucher David,Lally David R,Liao David S,Brown David Warren,Goldstein Debra,Marcus Dennis,Chan Derek G,Dhoot Dilsher,Tacite Domingo,Zalewski Dominik,Espana Edgar M,Lad Eleonora M,Souied Eric H,Suan Eric P,Eting Eva,Sola Federico Furno,de Bats Flore,Bandello Francesco,Gómez-Ulla Francisco,Devin François,Holz Frank G,Chen Fred K,Makkouk Fuad,Dyer Gawain,Spital George,Staurenghi Giovanni,Stoller Glenn,Cousins Gwen,Salehi-Had Hani,Agostini Hansjürgen,Eleftheriadis Haralabos,Weiss Harold,Sultan Harris C,Massé Hélène,Pearce Ian,Dias Indra,Barbazetto Irene,Rosenblatt Irit,Suñer Ivan J,Kovach Jaclyn L,Kaluzny Jakub,Borthwick James,Howard James G,Wong James,Ernest Jan,Němčanský Jan,Ysasaga Jason Edward,Handza Jason M,Moreno Javier Antonio Montero,Korobelnik Jean-François,Heier Jeffrey S,Arnold Jennifer J,Brown Jeremiah,Bafalluy Joaquin,Pearlman Joel,Pitcher John D,Kitchens John,Carlson John P,Gilhotra Jolly,Fein Jordana,Monés Jordi M,Luna José Domingo,Moreno José María Ruiz,Coney Joseph M,Sallum Juliana Maria Ferraz,Olsen Karl R,Blobner Katharina,Macoul Katherine A,Oh Kean T,Malik Khurram Javed,Hattenbach Lars-Olof,Kodjikian Laurent,Neto Laurentino Biccas,Singerman Lawrence J,Altay Lebriz,Sheck Leo-H,Feiner Leonard,Harris Lindsey D,Chishold Lionel D,Rao Llewelyn J,Nehemy Márcio Bittar,Elizalde Maria Jose Capella,Gamulescu Maria-Andreea,Saravia Mario J,Johnson Mark W,McKibbin Martin,Maccumber Mathew,Vidosevich Matko,Ohr Matthew P,Samuel Michael A,Singer Michael A,Cassell Michael,Dollin Michael,Elman Michael J,Ip Michael S,Goldstein Michaella,Busquets Miguel,Mititelu Mihai,Shah Milan,Veith Miroslav,Fineman Mitchell,Varano Monica,Christmas Nancy,Steinle Nathan C,Chaudhry Nauman,Chinskey Nicholas D,Eter Nicole,London Nikolas J S,Mathalone Nurit,Schlottmann Patricio G,Coady Patrick,Higgins Patrick M,Raskauskas Paul A,Yates Paul A,Bernstein Paul,Mitchell Paul,Monsour Paul,Raphaelian Paul V,Stanga Paulo E,Stodulka Pavel,Issa Peter Charbel,Pavan Peter,Ferrone Phil J,Oleksy Piotr,Abraham Prema,Mruthyunjaya Prithvi,Nguyen Quan Dong,Reddy Rahul K,Khurana Rahul N,Tuli Raman,Tadayoni Ramin,Katz Randy Steven,Arora Rashi,Schlingemann Reinier O,Rosen Richard B,Gale Richard,Scartozzi Richard,Isernharge Ricky,Singh Rishi P,Stoltz Robert A,Avery Robert L,Wirthlin Robert S,Guymer Robyn,Goldberg Roger A,Frenkel Ronald,Belfort Rubens Jr,Mohand-Said Saddek,Grisanti Salvatore,Razavi Sam,Fraser-Bell Samantha,Shah Sandeep N,Wickremasinghe Sanjeewa,Haug Sara Joy,Adrean Sean D,Priglinger Siegfried G,Esposti Simona Degli,Guest Stephen,Huddleston Stephen,Itty Sujit,Moon Suk Jin,Bhatia Sumit P,Gupta Sunil,Patel Sunil S,Garg Sunir J,Joshi Sunir,Nghiem-Buffet Sylvia,Johnson T Mark,Jaouni Tareq,Ach Thomas,Williams Thomas R,Sheidow Thomas,Cleland Timothy P,You Timothy T,Peto Tunde,Konidaris Vasileios,Gonzalez Victor H,Korda Vladimir,Freeman William R,Bridges William Z,Barak Yoreh,Zagorski Zbigniew,Yehoshua Zohar,Dubska Zora

Funder

Apellis Pharmaceuticals

Publisher

Elsevier BV

Subject

General Medicine

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