The safety of addition of nitrous oxide to general anaesthesia in at-risk patients having major non-cardiac surgery (ENIGMA-II): a randomised, single-blind trial

Author:

Myles Paul S,Leslie Kate,Chan Matthew T V,Forbes Andrew,Peyton Philip J,Paech Michael J,Beattie W Scott,Sessler Daniel I,Devereaux P J,Silbert Brendan,Schricker Thomas,Wallace Sophie

Funder

Australian National Health and Medical Research Council

Publisher

Elsevier BV

Subject

General Medicine

Reference36 articles.

1. Perioperative cardiac events in patients undergoing noncardiac surgery: a review of the magnitude of the problem, the pathophysiology of the events and methods to estimate and communicate risk;Devereaux;CMAJ,2005

2. Preoperative assessment of patients with known or suspected coronary disease;Mangano;N Engl J Med,1995

3. Perioperative increase in global blood flow to explicit defined goals and outcomes following surgery;Grocott;Cochrane Database Syst Rev,2012

4. Postoperative changes in procoagulant factors after major surgery;Lison;Blood Coagul Fibrinolysis,2011

5. Nitrous oxide-induced increased homocysteine concentrations are associated with increased postoperative myocardial ischemia in patients undergoing carotid endarterectomy;Badner;Anesth Analg,2000

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