Ixekizumab for the treatment of patients with active psoriatic arthritis and an inadequate response to tumour necrosis factor inhibitors: results from the 24-week randomised, double-blind, placebo-controlled period of the SPIRIT-P2 phase 3 trial

Author:

Nash Peter,Kirkham Bruce,Okada Masato,Rahman Proton,Combe Benard,Burmester Gerd-Ruediger,Adams David H,Kerr Lisa,Lee Chin,Shuler Catherine L,Genovese Mark,Ahmed Khalid,Alper Jeffrey,Barkham Nichol,Bennett Ralph E.,García Francisco Javier Blanco,Alonso Ricardo Blanco,Blumstein Howard B.,Brooks Michael S.,Burmester Gerd-Rüdiger,Cagnoli Patricia,Caldron Paul H.,Cantagrel Alain,Chen Der-Yuan,Churchill Melvin A.,Codding Christine E.,Combe Benard,Deane Peter M.G.,Del Giudice Jose,Deodhar Atul A.,Dhar Rajat K.,Dokoupilova Eva,Egan Rita M.,Everding Andrea,Galíndez Eva,Genovese Mark,Goddard David H.,Gottlieb Alice,Goupille Philippe,Griffin Robert M.,Gupta Ramesh C.,Hall Stephen,Hatti Kalpita,Howell Mary P.,Huang Yu-Huei,Jajoo Ramina,Janssen Namieta M.,Kiltz Uta,Kivitz Alan J.,Klein Steven J.,Korkosz Mariusz P.,Kotha Roshan,Kremer Joel M.,Lue Cummins,de la Fuente José Luis Marenco,Marzo-Ortega Helena,Masmitja Jordi Gratacós,Mease Philip J.,Meroni Pier Luigi,Mueller Eric C.,Nandagudi Anupama C.,Nash Peter,Fernández-Nebro Antonio,Neuwelt Clark M.,Orbai Ana Maria,Oza Meera R.,Parks Deborah L.,Pattanaik Debendra,Rell-Bakalarska Maria E.,Rosmarin David,Roussou Euthalia,Rychlewska-Hanczewksa Anna I.,Sikes David H.,Stack Michael T.,Sunkureddi Prashanth,Tahir Hasan,Thaçi Diamant,Tsai Tsen-Fang,Turkiewicz Anthony M.,Unger Leonore,Cabello Raúl Veiga,Wagner Ulf,Wei Cheng-Chung,Wells Alvin F.,Youssef Peter,Zielinska Agnieszka

Publisher

Elsevier BV

Subject

General Medicine

Reference29 articles.

1. Psoriatic arthritis;Ritchlin;N Engl J Med,2017

2. Psoriatic arthritis: epidemiology, clinical features, course, and outcome;Gladman;Ann Rheum Dis,2005

3. A short history of biological therapy for psoriatic arthritis;Mease;Clin Exp Rheumatol,2015

4. Pathogenic role of IL-17 in psoriasis and psoriatic arthritis;Chiricozzi;Actas Dermosifiliogr,2014

5. Increased numbers of circulating polyfunctional Th17 memory cells in patients with seronegative spondylarthritides;Jandus;Arthritis Rheum,2008

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