Lobeline and structurally simplified analogs exhibit differential agonist activity and sensitivity to antagonist blockade when compared to nicotine

Author:

Terry A.V,Williamson R,Gattu M,Beach J.W,McCurdy C.R,Sparks J.A,Pauly J.R

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Pharmacology

Reference48 articles.

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2. Effects of nicotinic agonists on the NMDA receptor;Aizenman;Brain Res.,1991

3. Arneric, S.P., Sullivan, J.P., Williams, M., 1995. Neuronal nicotinic acetylcholine receptors: novel targets for central nervous system therapeutics. In: Bloom, F.E., Kupfer, D.J. (Eds.), Psychopharmacology: The Fourth Generation of Progress. Raven Press, New York, pp. 95–110.

4. Bannon, A.W., Decker, M.W., Williams, M., Arneric, S.P., 1995. Psychotherapeutic potential of selective neuronal nicotinic acetylcholine receptor ligands. In: Domino, E.F. (Ed.). Brain Imaging of Nicotine and Tobacco Smoking. NPP Books, Ann Arbor, MI, pp. 311–334.

5. Relations between structure and nicotine-like activity: X-ray crystal structure analysis of (−)-cytisine and (−)-lobeline hydrochloride and a comparison with (−)-nicotine and other nicotine-like compounds;Barlow;Br. J. Pharmacol.,1989

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