Acute and chronic effects of the synthetic neuroactive steroid, ganaxolone, against the convulsive and lethal effects of pentylenetetrazol in seizure-kindled mice: comparison with diazepam and valproate

Author:

Gasior Maciej,Ungard Jesse T,Beekman Marjolein,Carter Richard B,Witkin Jeffrey M

Publisher

Elsevier BV

Subject

Cellular and Molecular Neuroscience,Pharmacology

Reference37 articles.

1. Potentiation of γ-aminobutyric-acid-activated chloride conductance by a steroid anaesthetic in cultured rat spinal neurons;Barker;Journal of Physiology,1987

2. Neurosteroids: of the nervous system, by the nervous system, for the nervous system;Baulieu;Recent Progress in Hormone Research,1997

3. Reversal of behavioral effects of pentylenetetrazol by the neuroactive steroid ganaxolone;Beekman;Journal of Pharmacology and Experimental Therapeutics,1998

4. Anticonvulsant steroids and the GABA/benzodiazepine receptor–chloride ionophore complex;Belelli;Neuroscience and Biobehavioral Review,1990

5. Unbalanced progesterone and estradiol secretion in catamenial epilepsy;Bonuccelli;Epilepsy Research,1989

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