Monitoring KRAS mutations in circulating DNA and tumor cells using digital droplet PCR during treatment of KRAS -mutated lung adenocarcinoma

Author:

Guibert Nicolas,Pradines Anne,Farella Magali,Casanova Anne,Gouin Sandrine,Keller LauraORCID,Favre GillesORCID,Mazieres Julien

Publisher

Elsevier BV

Subject

Cancer Research,Pulmonary and Respiratory Medicine,Oncology

Reference20 articles.

1. KRAS mutations in lung adenocarcinoma: molecular and epidemiological characteristics, methods for detection, and therapeutic strategy perspectives;Guibert;Curr. Mol. Med.,2015

2. Selective inhibition of oncogenic KRAS output with small molecules targeting the inactive state;Patricelli;Cancer Discov.,2016

3. Current challenges for detection of circulating tumor cells and cell-free circulating nucleic acids, and their characterization in non-small cell lung carcinoma patients. What is the best blood substrate for personalized medicine?;Ilie;Ann. Transl. Med.,2014

4. Detection of mutations in EGFR in circulating lung-cancer cells;Maheswaran;N. Engl. J. Med.,2008

5. ALK-gene rearrangement: a comparative analysis on circulating tumour cells and tumour tissue from patients with lung adenocarcinoma;Ilie;Ann. Oncol.,2012

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