Premature senescence induced by DNA demethylating agent (Decitabine) as therapeutic option for malignant pleural mesothelioma
Author:
Publisher
Elsevier BV
Subject
Cancer Research,Pulmonary and Respiratory Medicine,Oncology
Reference11 articles.
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2. Decitabine, differently from DNMT1 silencing, exerts its antiproliferative activity through p21 upregulation in malignant pleural mesothelioma (MPM) cells;Amatori;Lung Cancer,2009
3. Cellular senescence in cancer and aging;Collado;Cell,2007
4. Phase I study of Decitabine-mediated gene expression in patients with cancers involving the lungs, esophagus, or pleura;Schrump;Clin Cancer Res,2006
5. DNA methyltransferase inhibition in normal human fibroblasts induces a p21-dependent cell cycle withdrawal;Young;J Biol Chem,2001
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