ATF6α downregulation of PPARα promotes lipotoxicity-induced tubulointerstitial fibrosis

Author:

Jao Tzu-Ming,Nangaku Masaomi,Wu Chia-Hsien,Sugahara Mai,Saito Hisako,Maekawa Hiroshi,Ishimoto Yu,Aoe Mari,Inoue Tsuyoshi,Tanaka Tetsuhiro,Staels Bart,Mori Kazutoshi,Inagi Reiko

Funder

Japan Society for the Promotion of Science

Publisher

Elsevier BV

Subject

Nephrology

Reference48 articles.

1. Alteration of fatty acid oxidation in tubular epithelial cells: from acute kidney injury to renal fibrogenesis;Simon;Front Med (Lausanne),2015

2. Renal substrate metabolism;Wirthensohn;Physiol Rev,1986

3. Lipid nephrotoxicity in chronic progressive glomerular and tubulo-interstitial disease;Moorhead;Lancet,1982

4. Defective fatty acid oxidation in renal tubular epithelial cells has a key role in kidney fibrosis development;Kang;Nat Med,2015

5. Sirtuin1 maintains actin cytoskeleton by deacetylation of cortactin in injured podocytes;Motonishi;J Am Soc Nephrol,2015

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