Lipopolysaccharide induces filtrate leakage from renal tubular lumina into the interstitial space via a proximal tubular Toll-like receptor 4–dependent pathway and limits sensitivity to fluid therapy in mice
Author:
Funder
MIU Foundation
The Uehara Memorial Foundation
Next Generation Leading Research
Publisher
Elsevier BV
Subject
Nephrology
Reference25 articles.
1. Direct observations of change in function of the renal tubule caused by certain poisons;Richards;Trans Assoc Am Physicians,1929
2. The role of “leakage” of tubular fluid in anuria due to mercury poisoning;Bank;J Clin Invest,1967
3. Reduction of tubular flow rate as a mechanism of oliguria in the early phase of endotoxemia revealed by intravital imaging;Nakano;J Am Soc Nephrol,2015
4. Lipopolysaccharide directly alters renal tubule transport through distinct TLR4-dependent pathways in basolateral and apical membranes;Good;Am J Physiol Renal Physiol,2009
5. Regulation of renal sodium transporters during severe inflammation;Schmidt;J Am Soc Nephrol,2007
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