Production of functional human insulin-like growth factor binding proteins (IGFBPs) using recombinant expression in HEK293 cells

Author:

Wanscher Anne Sofie Molsted,Williamson Michael,Ebersole Tasja Wainani,Streicher Werner,Wikström Mats,Cazzamali Giuseppe

Funder

Novo Nordisk Foundation Center for Protein Research

Novo Nordisk-Chinese Academy of Science

Publisher

Elsevier BV

Subject

Biotechnology

Reference51 articles.

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2. Substrate specificity of the metalloproteinase pregnancy-associated plasma protein-A (PAPP-A) assessed by mutagenesis and analysis of synthetic peptides: substrate residues distant from the scissile bond are critical for proteolysis;Laursen;Biochem. J.,2002

3. Expression and characterization of a serine protease that preferentially cleaves insulin-like growth factor binding protein-5;Hou;J. Cell. Biochem.,2005

4. Insulin-like growth factors and their binding proteins: biological actions;Jones;Endocr. Rev.,1995

5. Surface-bound plasmin induces selective proteolysis of insulin-like-growth-factor (IGF)-binding protein-4 (IGFBP-4) and promotes autocrine IGF-II bio-availability in human colon-carcinoma cells;Remacle-Bonnet;Int. J. Cancer,1997

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