BAY 81-8973, a full-length recombinant factor VIII: Human heat shock protein 70 improves the manufacturing process without affecting clinical safety
Author:
Publisher
Elsevier BV
Subject
Biotechnology
Reference33 articles.
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3. Cell surface staining of recombinant factor VIII is reduced in apoptosis resistant BHK-21 cells;Ishaque;J. Biotechnol.,2008
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2. BAY 81‐8973 demonstrated efficacy, safety and joint status improvement in patients with severe haemophilia A in the LEOPOLD I extension for ≤2 years;European Journal of Haematology;2020-03-23
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4. Increased branching and sialylation of N-linked glycans correlate with an improved pharmacokinetic profile for BAY 81–8973 compared with other full-length rFVIII products;Drug Design, Development and Therapy;2019-03
Increased branching and sialylation of N-linked glycans correlate with an improved pharmacokinetic profile for BAY 81–8973 compared with other full-length rFVIII products
5. Recombinant Coagulation Factors and Thrombolytic Agents;Pharmaceutical Biotechnology;2019
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