Recombinant expression of Ixolaris, a Kunitz-type inhibitor from the tick salivary gland, for NMR studies
Author:
Funder
Fundação Carlos Chagas Filho de Amparo a Pesquisa do Estado do Rio de Janeiro (FAPERJ)
Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)
Publisher
Elsevier BV
Subject
Biotechnology
Reference28 articles.
1. In vitro mode of action and anti-thrombotic activity of boophilin, a multifunctional Kunitz protease inhibitor from the midgut of a tick vector of babesiosis, rhipicephalus microplus;Assumpção,2016
2. Nematode anticoagulant protein c2 reveals a site on factor Xa that is important for macromolecular substrate binding to human prothrombinase;Buddai;J. Biol. Chem.,2002
3. Fasxiator, a novel factor XIa inhibitor from snake venom, and its site-specific mutagenesis to improve potency and selectivity;Chen;J. Thromb. Haemost.,2015
4. Fuentes-Prior P.Tick-derived Kunitz-type inhibitors as antihemostatic factors;Corral-Rodríguez;Insect Biochem. Mol. Biol.,2009
5. Bacterial cell factories for recombinant protein production; expanding the catalogue;Ferrer-Miralles;Microb. Cell Fact.,2013
Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Small protease inhibitors in tick saliva and salivary glands and their role in tick-host-pathogen interactions;Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics;2020-02
2. NMR structure determination of Ixolaris and factor X(a) interaction reveals a noncanonical mechanism of Kunitz inhibition;Blood;2019-08-22
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