Removal of half antibody, hole-hole homodimer and aggregates during bispecific antibody purification using MMC ImpRes mixed-mode chromatography
Author:
Publisher
Elsevier BV
Subject
Biotechnology
Reference5 articles.
1. A brief introduction of IgG-like bispecific antibody purification: methods for removing product-related impurities;Li;Protein Expr. Purif.,2019
2. 'Knobs-into-holes' engineering of antibody CH3 domains for heavy chain heterodimerization;Ridgway;Protein Eng. Des. Sel.,1996
3. Monitoring removal of hole-hole homodimer by analytical hydrophobic interaction chromatography in purifying a bispecific antibody;Chen;Protein Expr. Purif.,2019
4. Polishing of Monoclonal Antibodies Using Capto™ MMC ImpRes in Bind and Elute Mode,2013
5. Capto™ MMC ImpRes,2015
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