Inhibitory effects of some steroidal 6-methylene derivatives on 5α-reductase activity in human and rat prostate-Reference-Cited by-同舟云学术

Inhibitory effects of some steroidal 6-methylene derivatives on 5α-reductase activity in human and rat prostate

Published:1983-05 Issue:5 Volume:18 Page:551-558
ISSN:0022-4731
Container-title:Journal of Steroid Biochemistry
language:en
Short-container-title:Journal of Steroid Biochemistry

Author:

Kadohama N.,Petrow V.,Lack L.,Sandberg A.A.

Publisher

Elsevier BV

Subject

Endocrinology,Biochemistry

Reference31 articles.

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4. Prostatic cancer. I. 6-Methylene-4-pregnen-3-ones as irreversible inhibitors of rat prostatic Δ4-3-ketosteroid 5α-reductase;Petrow;Steroids,1981

5. Petrow V., Wang Y., Lack L., Sandberg A. A. and Kadohama N.: Prostatic cancer. II. Inhibitors of rat prostatic Δ4-3-ketosteroid 5α-reductase derived from 6-methylene-4-androsten-3-one. Submitted for publication.

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2. 6-methylene progesterone is cytotoxic to human cancer cell lines independent of its 5-α-reductase activity;The Prostate;1995-01

3. LY207320 (6-methylene-4-pregnene-3,20-dione) inhibits testosterone biosynthesis, androgen uptake, 5α-reductase, and produces prostatic regression in male rats;The Prostate;1993

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5. Inhibition of rat liver steroid 5.alpha.-reductase by 3-androstene-3-carboxylic acids: mechanism of enzyme-inhibitor interaction;Biochemistry;1990-03-20