Ursolic acid inhibits the cholesterol biosynthesis and alleviates high fat diet-induced hypercholesterolemia via irreversible inhibition of HMGCS1 in vivo-Reference-Cited by-同舟云学术

Ursolic acid inhibits the cholesterol biosynthesis and alleviates high fat diet-induced hypercholesterolemia via irreversible inhibition of HMGCS1 in vivo

Published:2022-08 Issue: Volume:103 Page:154233
ISSN:0944-7113
Container-title:Phytomedicine
language:en
Short-container-title:Phytomedicine

Author:

Ma Xiaoyao,Bai Yongping,Liu Kaixin,Han Yiman,Zhang Jinling,Liu Yuteng,Hou Xiaotao,Hao Erwei,Hou Yuanyuan,Bai Gang

Publisher

Elsevier BV

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine

Reference32 articles.

1. Atorvastatin inhibits cholesterol-induced caspase-3 cleavage through down-regulation of p38 and up-regulation of Bcl-2 in the rat carotid artery;Bayatmakoo;Cardiovasc. J. Afr.,2017

2. Monolluma quadrangula protects against oxidative stress and modulates LDL receptor and fatty acid synthase gene expression in hypercholesterolemic rats;Bin-Jumah;Oxid. Med. Cell. Longev.,2018

3. Staphylococcus aureus 3-hydroxy-3-methylglutaryl-CoA synthase: crystal structure and mechanism;Campobasso;J. Biol. Chem.,2004

4. 3-Hydroxy-3-methylglutaryl-CoA synthase. A role for glutamate 95 in general acid/base catalysis of C-C bond formation;Chun;J. Biol. Chem.,2000

5. Chemoproteomics reveals baicalin activates hepatic CPT1 to ameliorate diet-induced obesity and hepatic steatosis;Dai;Proc. Natl. Acad. Sci. U. S. A.,2018

Cited by 14 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Hypolipidemic activity of phytochemical combinations: A mechanistic review of preclinical and clinical studies;Food Chemistry;2024-11

2. Disrupted gut microecology after high-dose 131I therapy and radioprotective effects of arachidonic acid supplementation;European Journal of Nuclear Medicine and Molecular Imaging;2024-04-02

3. Exploring Phytochemical Mechanisms in the Prevention of Cholesterol Dysregulation: A Review;Journal of Agricultural and Food Chemistry;2024-03-22

4. Key genes involved in nonalcoholic steatohepatitis improvement after bariatric surgery;Frontiers in Endocrinology;2024-02-26

5. The Complement Component 4 Binding Protein α Gene: A Versatile Immune Gene That Influences Lipid Metabolism in Bovine Mammary Epithelial Cell Lines;International Journal of Molecular Sciences;2024-02-17