The extract of Polygala fallax Hemsl. slows the progression of diabetic nephropathy by targeting TLR4 anti-inflammation and MMP-2/9-mediated anti-fibrosis in vitro-Reference-Cited by-同舟云学术

The extract of Polygala fallax Hemsl. slows the progression of diabetic nephropathy by targeting TLR4 anti-inflammation and MMP-2/9-mediated anti-fibrosis in vitro

Published:2022-09 Issue: Volume:104 Page:154251
ISSN:0944-7113
Container-title:Phytomedicine
language:en
Short-container-title:Phytomedicine

Author:

Wang Minhui,Liu Xinyan,Wang Zelong,Xu Qin

Publisher

Elsevier BV

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine

Reference24 articles.

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2. Persistent poor glycaemic control in individuals with type 2 diabetes in developing countries: 12 years of real-world evidence of the International Diabetes Management Practices Study (IDMPS);Aschner;Diabetologia,2020

3. Patient and disease characteristics of type-2 diabetes patients with or without chronic kidney disease: an analysis of the German DPV and DIVE databases;Bramlage;Cardiovasc Diabetol,2019

4. Serum matrix metalloproteinase-9, tissue inhibitor of metalloproteinase-1 and matrix metalloproteinase-9/neutrophil gelatinase-associated lipocalin complex levels in patients with early-stage diabetic nephropathy;Cakirca;Iran. J. Kidney Dis.,2018

5. Polygala fallax Hemsl combined with compound Sanqi granules relieves glomerulonephritis by regulating proliferation and apoptosis of glomerular mesangial cells;Chao;J. Int. Med. Res.,2020

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1. The mechanisms underlying Chinese medicines to treat inflammation in diabetic kidney disease;Journal of Ethnopharmacology;2024-10

2. Polygala fallax Hemsl. ameliorated high glucose-induced podocyte injury by modulating mitochondrial mPTP opening through the SIRT1/PGC-1α pathway;Archives of Physiology and Biochemistry;2024-09-02

3. Polygala fallax Hemsl polysaccharides alleviated alcoholic fatty liver disease by modifying lipid metabolism via AMPK;International Journal of Biological Macromolecules;2024-09

4. Mechanistic studies on the alleviation of ANIT-induced cholestatic liver injury by Polygala fallax Hemsl. polysaccharides;Journal of Ethnopharmacology;2024-06

5. Polygala Fallax Hemsl Ameliorates Renal Dysfunction and Podocyte Mitochondrial Oxidative Damage in Diabetic Rats by Activating the AMPK/SIRT1/PGC-1 α Signaling;J BIOL REG HOMEOS AG;2024