Astragaloside Ⅳ negatively regulates Gpr97-TPL2 signaling to protect against hyperhomocysteine-exacerbated sepsis associated acute kidney injury

Author:

Xu Jingge,Zhang Zhiyu,Ren Dongwen,Liu Luokun,Xing Haitao,Wang Dan,Wu Yuzheng,Zhang Yi,Chen Qian,Wang TaoORCID

Publisher

Elsevier BV

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine

Reference39 articles.

1. Amelioration of sepsis-induced acute kidney injury through inhibition of inflammatory cytokines and oxidative stress in dendritic cells and neutrophils respectively in mice: role of spleen tyrosine kinase signaling;Al-Harbi;Biochimie,2019

2. Acute kidney injury in sepsis;Bellomo;Intensive Care Med.,2017

3. Mitochondrial energetics in the kidney;Bhargava;Nat. Rev. Nephrol.,2017

4. Ginsenoside compound K ameliorates development of diabetic kidney disease through inhibiting TLR4 activation induced by microbially produced imidazole propionate;Chen;Int. J. Mol. Sci.,2022

5. GPR97 triggers inflammatory processes in human neutrophils via a macromolecular complex upstream of PAR2 activation;Chu;Nat. Commun.,2022

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