Paeoniflorin inhibits PRAS40 interaction with Raptor to activate mTORC1 to reverse excessive autophagy in airway epithelial cells for asthma

Author:

Cheng LinhuiORCID,Xiang Shuangdi,Yu Qiangqiang,Yu Tao,Sun Peng,Ye Chao,Xue Hanrong

Funder

National Natural Science Foundation of China

Publisher

Elsevier BV

Reference48 articles.

1. Underdiagnosis and overdiagnosis of asthma;Aaron;Am. J. Respir. Crit. Care Med.,2018

2. Immunologic mechanisms in asthma;Boonpiyathad;Semin. Immunol.,2019

3. Eosinophil-derived exosomes contribute to asthma remodelling by activating structural lung cells;Cañas;Clin. Exper. Allergy: J. British Soc. Allergy Clin. Immunol.,2018

4. Paeoniflorin ameliorates AGEs-induced mesangial cell injury through inhibiting RAGE/mTOR/autophagy pathway;Chen;Biomed. PharmacOther,2017

5. Allergy in severe asthma;Del Giacco;Allergy,2017

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