The abietane diterpenoid parvifloron D from Plectranthus ecklonii is a potent apoptotic inducer in human leukemia cells

Author:

Burmistrova Olga,Perdomo JuanORCID,Simões M. FátimaORCID,Rijo Patricia,Quintana JoséORCID,Estévez Francisco

Funder

European Regional Development Fund

Publisher

Elsevier BV

Subject

Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine

Reference23 articles.

1. Bcl-2-regulated apoptosis: mechanism and therapeutic potential;Adams;Curr. Opin. Immunol.,2007

2. Antiproliferative activity of abietane diterpenoids against human tumor cells;Burmistrova;J. Nat. Prod.,2013

3. Natural products: a continuing source of novel drug leads;Cragg;Biochim. Biophys. Acta,2013

4. The role of cell cycle regulation and apoptosis triggering in determining the sensitivity of leukemic cells to topoisomerase I and II inhibitors;Dubrez;Leukemia,1995

5. Abietane diterpenes induce cytotoxic effects in human pancreatic cancer cell line MIA PaCa-2 through different modes of action;Fronza;Phytochemistry,2012

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