Serum-free lentiviral vector production is compatible with medium-resident nuclease activity arising from adherent HEK293T host cells engineered with a nuclease-encoding transgene
Author:
Funder
Engineering and Physical Sciences Research Council
Publisher
Elsevier BV
Subject
Multidisciplinary
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1. Degradation of specific glycosaminoglycans improves transfection efficiency and vector production in transient lentiviral vector manufacturing processes;Frontiers in Bioengineering and Biotechnology;2024-06-26
2. Engineering an Autonucleolytic Mammalian Suspension Host Cell Line to Reduce DNA Impurity Levels in Serum-Free Lentiviral Process Streams;ACS Synthetic Biology;2024-01-24
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