Pan-cancer analysis reveals the prognostic and immunologic roles of cereblon and its significance for PROTAC design

Author:

Zhang Si-HanORCID,Zeng NaORCID,Sun Jian-Xuan,Liu Chen-Qian,Xu Jin-Zhou,Xu Meng-Yao,An Ye,Zhong Xing-Yu,Ma Si-Yang,He Hao-Dong,Xia Qi-Dong,Hu Jia,Wang Shao-Gang

Publisher

Elsevier BV

Subject

Multidisciplinary

Reference42 articles.

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2. Cereblon: a protein crucial to the multiple functions of immunomodulatory drugs as well as cell metabolism and disease generation;Shi;J. Immun. Res.,2017

3. Ligands for cereblon: 2017-2021 patent overview;Kazantsev;Expert Opin. Ther. Pat.,2022

4. The E3 ligase adapter cereblon targets the C-terminal cyclic imide degron;Ichikawa;Nature,2022

5. Delivery technologies for cancer immunotherapy;Riley;Nat. Rev. Drug Discov.,2019

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