Design and synthesis of novel enantiopure Bis(5-Isoxazolidine) derivatives: insights into their antioxidant and antimicrobial potential via in silico drug-likeness, pharmacokinetic, medicinal chemistry properties, and molecular docking studies

Author:

AL-Adhreai Arwa,ALSaeedy Mohammed,Alrabie Ali,Al-Qadsy Inas,Dawbaa Sam,Alaizeri ZabnAllah M.,Alhadlaq Hisham A.,Al-Kubati Abdulrahman,Ahamed Maqusood,Farooqui Mazahar

Funder

King Saud University

Publisher

Elsevier BV

Subject

Multidisciplinary

Reference37 articles.

1. In vitro antimicrobial and α-glucosidase inhibitory potential of enantiopure cycloalkylglycine derivatives: insights into their in silico pharmacokinetic, druglikeness, and medicinal chemistry properties;Kadri;J. Appl. Pharmaceut. Sci.,2020

2. Bioorganic Chemistry Novel enantiopure isoxazolidine and C -alkyl imine oxide derivatives as potential hypoglycemic agents : design , synthesis , dual inhibitors of α- amylase and α-glucosidase , ADMET and molecular docking study;Ghannay;Bioorg. Chem.,2020

3. Design, synthesis, molecular properties and in vitro antioxidant and antibacterial potential of novel enantiopure isoxazolidine derivatives;Ghannay;Arab. J. Chem.,2020

4. Bioorganic Chemistry Multifunctional isoxazolidine derivatives as α-amylase and α-glucosidase inhibitors;Ghabi;Bioorg. Chem.,2020

5. Synthesis and Characterization of 5-Substituted Novel Isoxazolidines Derived from 1 , 3-Dipolar Cycloaddition of Nitrones with Olefins : Studies of Antibacterial and Antifungal Activities Cycloaddition of Nitrones with Olefins;Kumar,2006

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