Lack of mitochondrial toxicity in CEM cells treated with carbovir

Author:

Parker William B,Shaddix S.C,Vince Robert,Bennett L.Lee

Publisher

Elsevier BV

Subject

Virology,Pharmacology

Reference27 articles.

1. Chen, C.-H. and Cheng, Y.-C. (1989) Delayed cytotoxicity and selective loss of mitochondrial DNA in cells treated with the anti-human immunodeficiency virus compound 2′,3′-dideoxycytidine. J. Biol. Chem. 264, 11 934–11 937.

2. Medina, D.J., Tsai, C.-H., Hsiung, G.D. and Cheng, Y.-C. (1994) Comparison of mitochondrial morphology, mitochondrial DNA content, and cell viability in cultured cells treated with three anti-human immunodeficiency virus dideoxynucleosides. Antimicrob. Agents Chemother. 38, 1824–1828.

3. Dalakas, M.C., Illa, I., Pezeshkpour, G.H., Laukaitis, J.P., Cohen, B. and Griffin, J.L. (1990) Mitochondrial myopathy caused by long-term zidovudine therapy. New Engl. J. Med. 322, 1098–1105.

4. Parker, W.B. and Cheng, Y.-C. (1994) Mitochondrial toxicity of antiviral nucleoside analogs. J. NIH Res. 6, 57–61.

5. Ono, K., Nakane, H., Herdewijn, P., Balzarini, J. and De Clercq, E. (1989) Differential inhibitory effects of several pyrimidine 2′,3′-dideoxynucleoside 5′-triphosphates on the activities of reverse transcriptase and various cellular DNA polymerases. Mol. Pharmacol. 35, 578–583.

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