[Translated article] Tirbanibulin: review of its novel mechanism of action and how it fits into the treatment of actinic keratosis

Author:

Gilaberte Y.,Fernández-Figueras M.T.

Publisher

Elsevier BV

Subject

Dermatology,Histology,Pathology and Forensic Medicine

Reference30 articles.

1. From actinic keratosis to squamous cell carcinoma: pathophysiology revisited;Fernandez Figueras;J Eur Acad Dermatol Venereol.,2017

2. Pathobiology of actinic keratosis: ultraviolet-dependent keratinocyte proliferation;Berman;J Am Acad Dermatol.,2013

3. Antitumor Effect of KX-01 through Inhibiting Src Family Kinases and Mitosis;Kim;Cancer Res Treat Off J Korean Cancer Assoc.,2017

4. Phase 3 Trials of Tirbanibulin Ointment for Actinic Keratosis;Blauvelt;N Engl J Med.,2021

5. Reversible binding of the anticancer drug KXO1 (tirbanibulin) to the colchicine-binding site of β-tubulin explains KXO1’s low clinical toxicity;Niu;J Biol Chem.,2019

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