Hypo-glycosylated human follicle-stimulating hormone (hFSH21/18) is much more active in vitro than fully-glycosylated hFSH (hFSH24)

Author:

Bousfield George R.,Butnev Vladimir Y.,Butnev Viktor Y.,Hiromasa Yasuaki,Harvey David J.,May Jeffrey V.

Publisher

Elsevier BV

Subject

Endocrinology,Molecular Biology,Biochemistry

Reference45 articles.

1. Insect cells as hosts for the expression of recombinant glycoproteins;Altmann;Glycoconj. J.,1999

2. Effect of different FSH isoforms on cyclic-AMP production by mouse cumulus-oocyte complexes: a time course study;Andersen;Mol. Hum. Reprod.,2001

3. Specific roles for the asparagine-linked carbohydrate residues of recombinant human follicle stimulating hormone in receptor binding and signal transduction;Bishop;J. Mol. Endocrinol.,1994

4. Both of the b-subunit carbohydrate residues of follicle-stimulating hormone determine the metabolic clearance rate and in vivo potency;Bishop;Endocrinology,1995

5. Purification of lutropin and follitropin in high yield from horse pituitary glands;Bousfield;J. Biol. Chem.,1984

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