Attenuation of mitochondrial and nuclear p38α signaling: A novel mechanism of estrogen neuroprotection in cerebral ischemia

Author:

Han Dong,Scott Erin L.,Dong Yan,Raz Limor,Wang Ruimin,Zhang Quanguang

Funder

American Heart Association

Foundation of President of Xuzhou Medical College

Publisher

Elsevier BV

Subject

Endocrinology,Molecular Biology,Biochemistry

Reference61 articles.

1. Cell surface estrogen receptor alpha is upregulated during subchronic metabolic stress and inhibits neuronal cell degeneration;Barbati;PLoS ONE,2012

2. Inhibition of p38 mitogen-activated protein kinase provides neuroprotection in cerebral focal ischemia;Barone;Med. Res. Rev,2001

3. Nuclear export of the stress-activated protein kinase p38 mediated by its substrate MAPKAP kinase-2;Ben-Levy;Curr. Biol,1998

4. [The up-regulation of p-p38 MAPK during the induction of brain ischemic tolerance induced by intermittent hypobaric hypoxia preconditioning in rats];Bi;Zhongguo Ying Yong Sheng Li Xue Za Zhi,2014

5. Apoptosis by cisplatin requires p53 mediated p38alpha MAPK activation through ROS generation;Bragado;Apoptosis,2007

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