Niacin-induced hyperglycemia is partially mediated via niacin receptor GPR109a in pancreatic islets-Reference-Cited by-同舟云学术

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Niacin-induced hyperglycemia is partially mediated via niacin receptor GPR109a in pancreatic islets

Published:2015-03 Issue: Volume:404 Page:56-66
ISSN:0303-7207
Container-title:Molecular and Cellular Endocrinology
language:en
Short-container-title:Molecular and Cellular Endocrinology

Author:

Chen Lihua,So Wing Yan,Li Stephen Y.T.,Cheng Qianni,Boucher Barbara J.,Leung Po Sing

Funder

Merck Sharp & Dohme

Research Grants Council of the Hong Kong Special Administrative Region, China

Publisher

Elsevier BV

Subject

Endocrinology,Molecular Biology,Biochemistry

Reference46 articles.

1. Pathophysiology of hyperlipidemia in diabetes mellitus;Abbate;J. Cardiovasc. Pharmacol,1990

2. Niacin restriction upregulates NADPH oxidase and reactive oxygen species (ROS) in human keratinocytes;Benavente;Free Radic. Biol. Med,2008

3. Nicotinic acid-induced flushing is mediated by activation of epidermal Langerhans cells;Benyo;Mol. Pharmacol,2006

4. A novel intronic peroxisome proliferator-activated receptor gamma enhancer in the uncoupling protein (UCP) 3 gene as a regulator of both UCP2 and -3 expression in adipocytes;Bugge;J. Biol. Chem,2010

5. Impaired beta-cell function in human aging: response to nicotinic acid-induced insulin resistance;Chang;J. Clin. Endocrinol. Metab,2006

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2. Niacin exacerbates β cell lipotoxicity in diet-induced obesity mice through upregulation of GPR109A and PPARγ2: Inhibition by incretin drugs;Frontiers in Endocrinology;2022-12-07

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